Despite large number of safe and effective contraception means, abortion stays a popular measure of birth control all over the world.
It is known that surgical abortion has negative consequences on female reproductive functions and health. Therefore modern women usually choose medical abortion as alternative method to surgical abortion, which is carried out at early stage pregnancy.
There are several abortion drugs with abortifacient effect. These are for example, abortifacient drugs, used for off-label pregnancy interruption. An overwhelming majority of abortion drugs are produced in pills for oral use, available under different trade names at local pharmacies.
Retail pharmacy networks also offer vaginal suppositories with abortifacient effect, prescribed:
* in addition to abortion pills or as an independent abortion drug;
* for expansion and softening of the cervix before surgical abortion.
Usually oral abortion pills are used for medical abortion. Herewith each woman should know that these pills are only for use under supervision of health professional, regardless of types of abortion pills.
Types of abortion pills
* Synthetic steroids with antiprogestational effect
* Synthetic prostaglandin analoges
The results of clinical trials suggest that the use of legal abortion pills is one of the safest and reliable methods of interrupting pregnancy. The truth is that abortion pills have been used to interrupt the uterine pregnancy for over 10 years now. Moreover, number of countries where abortion pills, approved by the national health system, is constantly growing.
One of the first oral abortion drugs, approved by the FDA in 2002, was Mifepristone. Noteworthy that the USA and New Zealand were among few countries, where Mifepristone synthetic steroid have been administered for medical abortion at early pregnancy up to 2007.
France and Sweden became two first EU member countries, which have approved abortion pills for interrupting pregnancy. In 2012, Mifepristone was included into ARTG in Australia.
How do abortion pills help to interrupt pregnancy?
Antiprogestational synthetic steroids (including Mifepristone) effect is to inhibit progesterone on the myometrium and endometrium, thus:
* inducing the frequency and strength of spontaneous uterine contractions;
* stimulating the removal of uterine content.
In overwhelming majority cases, abortion takes place within the first three days after using Mifepristone abortion pills. If abortion does not happen in two days after the intake of Mifepristone synthetic steroid, on the third day woman should take another abortion pill containing synthetic prostaglandin analogue (like Misoprostol).
Misoprostol several times increases the probability of anticipated effect, thereby reducing the risk of surgical abortion. If 14 days after the intake of the first dose pregnancy was not interrupted, woman should consult a doctor about the possible use of some alternative methods of early abortion.
As an alternative to abortion pills, women can be prescribed with vaginal suppositories containing prostaglandin analogues (for example, Dinoprostone). Unlike abortion pills, which can be taken maximum in the seventh week of pregnancy, vaginal suppositories can be used for non-surgical abortion from 12 to 20 weeks pregnancy.
No less important is the fact that oral pills have been prescribed for medical abortion quite recently. As for the vaginal suppositories, they have been prescribed for over 35 years now. Thus vaginal suppositories is a conservative method of early abortion, so most of doctors recommend their patients to use modern effective and safe oral abortion pills.