Lower back pain relief

Episodes of back pain occur in more than 80% of people at least once in their life. Soreness of this type is one of the most common complaints faced by therapists, neurologists and physicians of other specialties.

There are a number of problems that can lead to lower back pain. Relief from pain should happen timely and take into account causes of occurrence of disease states.

The main causes of discomfort in the lower back are:

  • injuries to muscles, ligaments or joints
  • degenerative changes in the spine
  • narrowing of the spinal canal
  • low bone mass and deterioration of bone tissue
  • fibromyalgia syndrome

Relatively rare causes of lower back pain can be neurological and infectious diseases, ankylosing spondylitis, vertebral fractures, vertebral tumors and diseases of the internal organs.

It is normal to feel lower back soreness, especially for physically active people. This happens due to the body’s natural reaction to microtrauma of soft tissues. Workouts, sharp movements and weight lifting are the most common causes of light lower back pain.

Pain relief in humans can be pleasurable and rewarding. Simple exercises aimed at strengthening of the muscular corset and normalization of the blood supply can be performed at home or at work. To do this, you do not need to have special knowledge and spend a lot of time.

Physical exercises will relieve back pain and will help reduce the likelihood of injuries in the future. They can be performed by a person of any age and with any level of physical fitness. Type of injury and the person’s age should be taken into account when choosing intensity and duration of exercise.

Heat helps to speed up healing of soft tissues in the long term. Application of ice or cold compresses reduces inflammation immediately after the pulled muscle.

If light pain does not disappear or worsens, it is better to consult a physiotherapist. Such specialists help people affected by injuries, diseases, disability, as well as women experiencing lower back pain during pregnancy.

Pain relief and other distressing symptoms contribute to rapid recovery and strengthening of muscle tissue. As a result, quality of life is improved in people and they are able to stay healthy as long as possible.

Physiotherapists apply their skills and knowledge not only to reduce back pain. Physiotherapy is based on involvement of the person in the process of helping himself. Consultation with such specialists will allow to learn more about prevention of musculoskeletal, neurological, cardiovascular, respiratory and other disorders.

A qualified physiotherapist will find out about the person’s existing or past health problems. Then the physiotherapist will determine the cause of lower back soreness, will offer treatment and help prevent development of further health problems. The patient can be offered a number of procedures that have proven their effectiveness in dealing with back pain, such as massages, acupuncture or yoga.

Tips for lower back pain relief will help to remain employable and physically active. However, if soreness of the back is caused by moderate or severe soft tissue injuries, skeletal injuries, stenosis, osteoporosis or other diseases, use of the following medications can be required:

  • NSAIDs
  • Weak analgesics
  • Vasoactive drugs
  • Muscle relaxants
  • Opioid analgesics

NSAIDs or weak analgesics are most often used for treatment of patients suffering from back pain. Such drugs have analgesic effect, reduce physical suffering and rarely cause side effects.

Unlike other drugs, NSAIDs provide analgesic, as well as anti-inflammatory effects. Therefore, if the disease states are caused by inflammation, NSAIDs are recommended.

The main mechanism of NSAIDs action is to block prostaglandins production (mediators of inflammatory pain). During use of such drugs, the amount of prostaglandins in the inflammatory focus is rapidly decreasing and physical suffering disappears.

Lower back pain relief is achieved within a few hours after taking medications of the NSAIDs group. Use of recommended doses of NSAIDs several times per day will allow to maintain a stable analgesic effect.

NSAIDs are considered safe drugs, but sometimes adverse reactions occur during their use. The most frequent of them are heartburn, dry mouth, gastric ulcer and other gastrointestinal side effects.

NSAIDs or mild analgesics can be taken in combination with vasoactive drugs, muscle relaxants and medications of other types. Their application helps:

  • Reduce duration of treatment
  • Reduce risk of developing adverse reactions
  • Reduce excess muscle strain
  • Improve functional capacity of the musculoskeletal system
  • Maintain activity in everyday life

If physical suffering is intolerable or musculoskeletal disease is incurable, opioid analgesics or other powerful medications for lower back pain relief are used. Medications of this type are very effective, although their use is associated with certain risks.

Patients taking opioid analgesics may become addicted to them. Excess of the recommended dose causes a feeling of euphoria. Because of high risk of addiction and other side effects, such drugs are sold by prescription only.

It often happens that opioids are the only method of acute or chronic back pain relief. When such analgesics are taken under careful supervision of the treating physician, opioids are a safe and effective method of reducing physical suffering.

List of pain medications

Effective pain management is a complex task that requires a many-sided approach using different methods and medicines. In most cases, pharmacotherapy is the most convenient and effective method of managing physical suffering.

The list of pain medications includes several hundred names. All these medications can be divided into the following groups:

  • Mild analgesics
  • Weak opioid analgesics
  • Opioid drugs

Pharmacotherapy of physical suffering and discomfort begins with the use of mild analgesics. If the medication turns ineffective, powerful analgesics are prescribed. This approach provides a stepwise selection of analgesics from a weaker to a stronger one.

The list of pain medications is headed by Acetaminophen (Paracetamol). This is the most famous and often used mild analgesic in the US and Europe.

Pain treatment begins namely with Acetaminophen in headache, migraine, neuralgia, as well as in pain caused by injuries, rheumatic diseases and colds.

Acetaminophen has many advantages, the most important of which are:

  • Over-the-counter sales
  • Rapid relief of soreness
  • Well tolerated by patients
  • Excellent efficiency and safety profile
  • Possibility of taking with other medicines

Acetaminophen does not possess a significant anti-inflammatory effect, which can be attributed to the shortcomings of this medication.

Pain can be caused or accompanied by inflammation. If this is the case, it is recommended to use Nonsteroidal Anti-Inflammatory Drugs (NSAIDs). Drugs of this type possess anti-inflammatory, antipyretic and analgesic effects.

Today, patients have an access to a wide range of medicines for inflammation and pain. The list of NSAIDs contains dozens of pain medications, including:

  • Ketorolac
  • Etodolac
  • Ketoprofen
  • Diclofenac

Ketorolac is an effective analgesic, yet it does have several drawbacks. Due to the risks of gastrointestinal and cardiovascular side effects, this medication is prescribed only for short-term use.

Ketorolac solution for injection should be used for up to 2 days. The maximum duration of treatment with Ketorolac tablets is 5 days.

Etodolac is included in the list of pain medications, intended for long-term use. This medicine allows monitoring chronic or acute pain of inflammatory origin.

The use of Etodolac is limited to a narrow range of indications:

  • Rheumatoid arthritis
  • Osteoarthritis

Etodolac is not indicated for the treatment of physical suffering in patients under 18 years of age. During the period of use of this NSAIDs, the elderly often experience gastrointestinal and other side effects.

Ketoprofen gel is used to treat soreness in patients over 12 years of age, adults and the elderly. The gel alleviates physical suffering and reduces inflammation, associated with soft tissue injuries.

Ketoprofen capsules are recommended to relieve suffering in people with rheumatoid diseases. Patients, who take Ketoprofen, notice increase in mobility and an improvement in life quality.

Diclofenac takes pride of place in the list of pain medications. This drug is used to control all grades of inflammation and pain in a wide range of conditions.

Indications for Diclofenac use are:

  • Migraine attacks
  • Diseases of the joints
  • Acute locomotor disorders
  • Inflammation and pain in minor surgery

Diclofenac is used in conjunction with other pain medications, including with stronger ones (e.g. Codeine). Combined use of drugs will allow controlling mild or moderate soreness.

If mild analgesics fail to alleviate physical suffering, weak opioid analgesics are prescribed. Drugs of this type are indicated for the management of acute or chronic pain caused by bone fractures, injuries, soft tissue burns and severe diseases.

The list of pain medications, used to treat moderate to severe physical suffering, includes:

  • Codeine
  • Dihydrocodeine
  • Tramadol

Weak opioid analgesics are usually taken 3-4 times a day. The doses should be taken at approximately equal time intervals. This allows maintaining a stable concentration of medications in the blood and providing a long-term pain relief.

For analgesia, sustained-release capsules can be used, like Maxitram SR (Tramadol). If this is the case, pain medications are taken 2 times a day, usually in the morning and in the evening. A minimum of 8 hours should pass between the dosing.

In some countries, you can buy Codeine oral solution. This medicine is not used to treat pain. It is indicated to reduce the symptoms of dry or irritating cough.

Weak opioid analgesics can cause euphoria, depression, hallucinations, drowsiness, nightmares, headache and other side effects.

All medications of this type are available for sale on prescription. If they don’t provide pain management, more powerful pain medications should be used.

The list of opioid drugs includes:

  • Pethidine
  • Levorphanol
  • Methadone
  • Morphine
  • Pentazocine
  • Buprenorphine
  • Hydromorphone

These drugs are used to relieve moderate to severe pain. If soreness is acute, patients are prescribed tablets, oral solution or solution for injections. Capsules and sustained-release tablets allow you controlling chronic pain.

The frequency of opioid drugs intake depends on the indications and the therapeutic response. As a rule, a minimum interval of 3 hours should be observed between the doses.

The use of opioid drugs is associated with an increased risk of side effects. The list of side effects of opioids includes respiratory depression, involuntary muscle contractions, drowsiness, dizziness, insomnia, constipation, nausea, anorexia and dry mouth.

During the use of opioids, a physical or psychological dependence on these drugs may develop. Therefore, opioids should be taken as little time, as possible.

The list of pain medications includes opioids supplied in the form of transdermal patches, like Bupeaze (Buprenorphine). Such patches are attached to the skin and gradually release the active substance.

Transdermal patches that include opioids are suitable for the treatment of chronic pain, for example, in cancer. During the period of the patches use, side effects do not manifest as often as they do, when people use tablets or injections.

Fioricet side effects

After the administration of the combined analgesic Fioricet, side effects may occur. However, they are mostly eliminated in one of the following ways: by changing the dosage, by replacing the drug with another analgesic, or by using other methods of anti-migraine therapy.

Unlike other potentially life-threatening pain medications, Fioricet does not have a pronounced negative impact and is well tolerated by patients. The onset of unwanted reactions is not an occasion for self-abolition of the drug.

The most common Fioricet side effects can be divided into two groups:

  • Gastrointestinal: nausea, emesis and stomach cramps
  • Psychiatric: drowsiness, lightheadedness, dizziness and confusion

Still, even if some adverse reactions are indicated in the instructions as “frequently observed”, they not necessarily arise in each individual patient. The negative impact of Fioricet can manifest only in 1 of 10 people who take the medicine.

In very rare cases, the side effects of Fioricet can occur on an ongoing basis. In addition to information on the frequency of occurrence, it is important to know how serious is an undesirable effect for your body. All listed adverse reactions of Fioricet are frequent, yet easily tolerable.

The frequency of occurrence and severity of adverse reactions are influenced by such factors, as:

  • coexisting illnesses
  • drug interactions
  • dosage and administration route

In clinical studies, the gastrointestinal side effects of Fioricet were less common than with other analgesics. Nevertheless, digestion problems significantly worsen patient’s life quality and require careful monitoring of patient’s condition.

Dopamine is one of the major neurotransmitters, involved in the pathogenesis of nausea and vomiting. Fioricet has a significant effect on AMPA receptors, which play a key role in maintaining the concentration of the neurotransmitter. Dopamine level surges contribute to sickness and vomiting – the most frequent gastrointestinal side effects of the drug.

Gastrointestinal intolerance is a common event in Fioricet treatment. Nausea and vomiting are the most serious gastrointestinal effects of the drug use in 70-80% of patients. The number of attacks of nausea and emesis may increase due to the fact that Fioricet tablets or capsules should be taken several times a day.

Following the nausea and vomiting, the list of the most common gastrointestinal side effects of Fioricet indicates gastric colic and diarrhea. The severity of adverse reactions from the gastrointestinal tract varies depending on the dose of Fioricet and the individual patient’s characteristics. However, people does not need additional antiemetic therapy while using this analgesic.

The variety of therapeutic effects of Fioricet (analgesic, psychostimulating, vasodilating and others) explains the fact that the negative effect of the drug on the nervous system is more pronounced, than that on the digestive system.

After the ingestion, Fioricet chemically reacts with sodium ions. As a result, the concentration of sodium salt in the body decreases. Deficiency of sodium causes the disturbance of circulation of neurotransmitters norepinephrine, serotonin and others.

Deficiency of neurotransmitters is the reason for such psychical side effects of Fioricet, as drowsiness, decreased alertness, lightheadedness and a sense of intoxication.

Drowsiness and reduced vigilance arise only at the initial stage of Fioricet treatment. The more the patient’s body adapts to the drug action, the fewer side effects of Fioricet will manifest. However, Fioricet is capable of rarely causing long-term problems with sleep or mental state, due to which some patients are forced to stop taking the drug.

Patients, who experience unusual sleepiness while using Fioricet, should:

  • reduce the dose of the drug;
  • combine rest with moderate physical activity;
  • refrain from prolonged driving and control of complex machinery.

Rare psychic side effects of Fioricet, such as overexcitation, fatigue, are possible with an overdose of the drug. High doses of Fioricet may rarely cause hallucinations.

Unlike other combined analgesics, which are characterized by increased cardiotoxicity, Fioricet causes almost no cardiovascular side effects. When the drug is used in therapeutic doses, unwanted reactions from the cardiovascular system are not clinically significant.

Negative effects on the cardiovascular system are observed only in patients, who suffer from bronchial obstruction. Yet, the risk of cardiotoxicity significantly increases, if you take Fioricet with other pain medications.

Rare, but potentially harmful to the health side effects of Fioricet are: fainting, anaphylactic shock, serotonin syndrome, seizures, impaired renal function or hepatotoxicity.

The risk of these unwanted reactions is usually very low – less than in 1 of 100 people. Therefore, patients should not fear of the negative effects of Fioricet in advance.

Fioricet does not contribute to a weight gain. Conversely, this combined analgesic can lead to loss of appetite and a slight weight loss. Some unwanted reactions are so weak that they can hardly be noticed. Minor side effects of Fioricet are dry mouth, heartburn, fatigue, nasal congestion or tinnitus.

Chronic pain

Unlike the usual pain symptoms that go away with time, chronic pain can last from 1-3 months to many years. The patient’s suffering can be associated with an existing pathological process or a post-traumatic condition.

Chronic pain is a complex clinical problem in many fields of medicine. Gynecologists, traumatologists, neurologists, oncologists and other doctors are facing the problem of adequate analgesic therapy.

The causes of chronic pain can be:

  • severe injuries and traumas
  • lesions of the peripheral nervous system
  • serious diseases, including cancer

The most important characteristic of chronic pain is that it is always subjective. The attending physician is not in a position to accurately diagnose or assess the emotional suffering of the patient with the help of objective scoring scales.

People are mostly capable of independently determining the degree of emotional and physical suffering. Despite the subjectivity of such assessment of pain intensity, this method most often corresponds to its actual level.

Treating physicians distinguish the following types of chronic pain:

  1. Nociceptive:
  • somatic (damage to bones or soft tissues)
  • visceral (internal damage)
  1. Neuropathic (overexcitation or damage to nerve structures)
  2. Psychogenic (emotional or muscular overload on a background of depression)

A patient may suffer from one or more types of chronic pain, each of which requires a specific approach to therapy. Classification of unpleasant sensory sensations helps to establish which medication can be most effective for a particular patient.

Treatment of chronic pain syndrome should be adapted for each individual patient. To alleviate suffering, doctors use analgesics. The choice of chronic pain killers is determined by several factors, the main ones being the etiology, intensity and type of pain, as well as the individual characteristics of the patient.

The first-line drugs in the therapy of nociceptive pain are non-narcotic analgesics, including NSAID and Paracetamol. With moderate severity of neuropathic pain symptoms, opioid analgesics are used.

A peculiarity of psychogenic pain is that it occurs without any organic damage. Many medical specialists in the diagnosis of diseases note the relationship between chronic pain and depression. Psychological factors have a significant impact on physical and emotional excitement. In turn, the psychological balance of a person depends on the degree of emotional and physical suffering.

The appearance of depression signs means that a person misunderstands the cause of physical discomfort and unreasonably considers his situation to be extremely difficult. Another reason for the onset of depression may be the fact that chronic pain significantly reduces the patient’s life quality. To overcome emotional distress, people first require the help of a psychologist or psychiatrist, while the analgesic therapy becomes a secondary measure.

Regardless of the type and severity of chronic pain, adjuvant therapy should be used together with analgesics. This is an auxiliary treatment of pain symptoms, aimed at increasing the effectiveness of analgesics. Adjuvant analgesics can be anxiolytics, antidepressants, antipsychotics, anticonvulsants and other drugs.

Problems that can arise during the therapy of chronic pain:

  • opioid dependence
  • side effects of drugs
  • polypharmacy (unjustified intake of several analgesics at the same time)

Men and women are equally susceptible to one or another chronic pain symptom. Fibromyalgia, which is a symmetrical physical discomfort throughout the entire body, is characteristic for men. Chronic pain symptoms in fibromyalgia are local or generalized increase in sensitivity to pathological and normal stimuli.

Chronic pain in women is often caused by adenomyosis, which is a pathological proliferation of the endometrium of the uterus. Characteristic signs of adenomyosis are:

  • infertility
  • chronic pelvic pain
  • menstrual disorder
  • disorders of the pelvic organs functioning

Relief of physical and emotional suffering in pregnant women is complicated by the fact that many drugs are contraindicated in women during the period of gestation. To reduce the risk of negative effects of drugs on the mother and child, pregnant women should be prescribed analgesics in case of emergency and only under the supervision of the attending physician.

The treatment of chronic pain is an absolute necessity, because it:

  • limits the person’s mobility;
  • significantly reduces the patient’s life quality;
  • negatively affects social activity;
  • causes mental and emotional disorders, the disintegration of the central nervous system activity.

Thus, chronic pain symptoms should be arrested, regardless of the severity and causes of their onset. Adequate and timely analgesic therapy reduces the frequency of exacerbations and the emergence of unpleasant sensory and emotional experiences.

Best pain reliever

As of today, no single approach exists in clinical practice for prescribing pain killers. It is impossible to select the best pain reliever, which would be equally effective for alleviating physical and emotional suffering for each and every patient.

Before the attending physician prescribes one or another analgesic, he should inform the patient about the properties of the drug, its therapeutic action and possible side effects. Timely prescription of the drug helps to quickly eliminate the pain symptoms.

For an adequate analgesia, the best pain reliever should have the following characteristics:

  • convenient dosing schedule;
  • optimal method of application for the patient;
  • fast analgesic effect, with a duration of at least 4 hours;
  • low systemic toxicity and minimal risk of side effects;
  • elimination of not only pain, but also somatic symptoms, like inflammation, edema, etc.
  • if necessary, to provide additional effects to anaesthetizing action, like anti-inflammatory, antipyretic, etc.

An adequate analgesic effect depends on the type and degree of pain intensity, as well as on the pharmacological class of the drug. For example, the best pain reliever for arthritis can become one of the non-steroidal anti-inflammatory drugs (NSAID) – Diclofenac, Ibuprofen and others. Narcotic (opioid) drugs, such as Morphine or Tramadol, are an excellent treatment option for chronic and violent attacks of pain.

Best pain reliever for back pain

The problem of back pain is still unexplored. To date, there is no treatment methods that would provide complete relief from emotional and physical suffering. Therefore, it is difficult to determine which of the drugs is the best pain reliever for back pain.

The main principle of back pain pharmacotherapy is the prescription of several drugs from different pharmacological groups. Currently, solving the problem of back pain by using only one drug is almost impossible. The choice of one or another drug for back pain should be based on knowledge of the drugs’ action mechanisms.

Depending on the reasons for the occurrence of emotional and physical suffering, the best pain reliever for back pain can be:

  • in myofascial pain syndrome – local anesthetic (Lidocaine)
  • in local muscle hypertension – one of the muscle relaxants: Tizanidine, Tolperisone or Baclofen;
  • in peripheral lesions of the spine – an opioid medication (Hydrocodone, Oxycodone) or an NSAID (Diclofenac, Meloxicam).

Best pain reliever for oncological pain

Relief of chronic pain syndrome in patients with oncological diseases is the main task of opioid drugs. To date, oncologists have about 60 different narcotic drugs, each of which can become the best pain reliever for oncological pain.

Due to the optimal therapeutic characteristics, Tramadol is the drug of choice for the relief of oncological pain. Oral opioid has a central and peripheral analgesic effect, and enhances the effect of sedatives, as well.

The prescription of the drugs, based on their mode of administration, is one of the possible strategies for alleviating the suffering of cancer patients. The best pain reliever for oncological pain, other than Tramadol, may also be injectable Trimeperidine or transdermal Fentanyl.

Best pain reliever for headache

Even though headache is not a serious clinical problem, it is one of the frequent reasons for contacting therapists and general practitioners. The drugs of choice for the treatment of headache are NSAID, as well as Paracetamol.

Aspirin is more common, than any other NSAID used for headache pharmacotherapy. The mechanism of its analgesic action consists of two components:

  • peripheral – increasing the threshold of pain sensitivity
  • central – inhibition of pain impulses along the nervous pathways of the spinal cord

A significant disadvantage of Aspirin, like of any other NSAID, is the ceiling effect, that is, the upping of the dose above the therapeutic dose does not increase the analgesic effect, while the severity of adverse reactions increases significantly.

Paracetamol is another drug that, according to popular opinion, is the best pain reliever for headache. It is a non-narcotic drug. However, Paracetamol does not belong to the NSAID, although it has similar therapeutic properties.

The reasons why Paracetamol is the best pain reliever for headache:

  • can be used by all patients, regardless of age;
  • significantly limits the severity of pain syndrome, reduces the intensity of pain impulses;
  • significantly reduces the need for the use of strong analgesics, for example, opiates.

Causes of resistance to analgesia and ways to overcome it

Medications are not always able to relieve pain. Even if the attending physician prescribed the best pain reliever, the patient may not experience relief from emotional and physical suffering. The reasons why analgesic therapy may be ineffective:

  • development of tolerance (with the use of narcotic drugs);
  • progression of the underlying disease and increase in pain intensity;
  • disruption of the drug absorption, which can arise because of gastrointestinal tract disorders;
  • incorrect diagnosis, in which the attending physician did not take into account the patient’s somatic diseases (stomach ulcers, allergies and others).

The ineffectiveness of the analgesic therapy does not mean that the patient will always experience painful or unpleasant sensations of pain. There are several ways to revise and correct the dosing regimen of pain medications:

  • titration of the drug dose;
  • change of dosage forms (for example, tablets for injections);
  • smooth transition from a weak analgesic to a stronger one (for example, from NSAID to opiate);
  • combining the use of drugs with non-drug treatment of pain: massage, manual therapy, etc.
  • using drugs for adjuvant pain therapy: antidepressants, antipsychotics, anticonvulsants, etc.

Choosing the best pain reliever is a difficult task. When prescribing an analgesic, it is important to strike a balance between their efficacy and the risk of side effects, while in combined therapy, to consider the possibility of drug interactions.

Erectile tissue that contains the urethra

Male reproductive organ is composed of the erectile tissue and contains the urethra. Another important element of the sex organ is the deep artery of the penis, which delivers blood to the erectile tissue.

The urethra consists of smooth muscles and essentially is a narrow tube. The main function of the urethra is the bladder emptying and the transfer of male germ cells outside during the ejaculation. The urinary tract in the female body does not have any direct reproductive functions.

Switching between the two functions of the male urethra goes automatically. During sexual arousal, blood flow increases, an erection occurs and the ejaculation takes place.

The main task that the erectile tissue performs is to ensure the erection process in the male sexual organ. This process enables the transfer of the genetic material from the male body into the female egg.

The male sex organ has three expandable erectile tissues of two different types. They are similar in function and structure, yet they do have some important differences. For example, one of them surrounds the urethra.

  • Erectile tissue that contains the urethra is called the corpus spongiosum.
  • Erectile tissue also forms two tubular structures, which are called corpora cavernosa.

Erectile tissue forms cylindrical bodies, which are located along the reproductive organ. The two corpora cavernosa are located on the sides and at the top of the penis. Corpus spongiosum is located below and between the corpora cavernosa.

The erectile tissue is composed of many small and interconnected cavities. In certain circumstances, such as in response to sexual stimulation, the erectile tissue cavities are engorged with blood.

Due to the sexual arousal and the increased blood flow, the primary sex organ increases in size, and becomes firm and erect. Man has the possibility to start and complete a sexual intercourse.

It should be noted that the erectile tissue contains major part of the blood in erection period. Urethra, skin, arteries, and other parts of the male reproductive organ are elastic and easily grow in size.

Achieving an erection that is sufficient for a having a sexual intercourse is the only basic function of corpora cavernosa. Therefore, most of blood (approximately 90%) is stored in the two cylindrical bodies.

Corpus spongiosum performs several functions. This tissue also accumulates blood cells, yet in smaller quantities, compared to the corpora cavernosa. Besides achieving an erection, another function of this cylindrical body is to prevent the compression of the urethra during an intercourse.

The tubular bodies contain blood throughout the entire sexual activity period. When the sexual act is completed, male body releases substances that help reduce the erectile process.

Reverse flow of blood from the cylindrical bodies is carried out via the venous plexus. It should be noted that the venous plexus are compressed during the sexual arousal and the increase of the tubular body size.

This delays the outflow of the blood from the erectile tissue. The urethra passes the male sex cells, immediately after which the process of blood flow starts.

Normal functioning of the tubular bodies has a direct impact on the sexual life of men. Poor blood flow, increased blood outflow from the corpus cavernosum or nerve tissue damages can cause sexual dysfunction.

Sexual function often worsens in older men. Low levels of physical activity, cardiovascular disease, smoking, and high intake of fatty foods increase the risk of sexual dysfunction.

Erectile dysfunction is not a severe disease, yet it can significantly worsen the mental condition of men. Approximately 20% of US men aged 20 and more have regular problems with erection. More than half of men over the age of 40 suffer from erectile dysfunction.

The discovery of the PDE-5 inhibitors became a true revolution in the issue of the erectile dysfunction treatment. In 1998, Sildenafil (Viagra) hit the market. In subsequent years, Vardenafil, Tadalafil and Avanafil went on sale.

Corpora cavernosa and the erectile tissue that contains the urethra quickly respond to the appearance the PDE-5 inhibitors in the blood. The erection occurs within 30-60 minutes after the oral administration of PDE-5 inhibitors.

Sildenafil, Vardenafil, Tadalafil and Avanafil have the same mechanism of action. After the ingestion of the drug, cyclic guanosine monophosphate (cGMP) accumulates in the erectile tissue. After the sexual excitement, blood flow increases and an erection can follow.

The duration of the PDE-5 inhibitors action differs significantly. Sildenafil can cause an erection within about 5 hours after administration. Tadalafil works for approximately 36 hours.

All PDE5 inhibitors are highly effective drugs. They have a good safety profile and rarely cause any side effects. Therefore, these drugs have found their wide application in the treatment of the erectile dysfunction.

If the erectile tissue that contains the urethra is not adequately responding to one of the drugs for the erectile dysfunction treatment, man can be recommended another medication. The availability of several PDE-5 inhibitors allows choosing the one that best suits each individual patient.

Millions of PDE5 inhibitors doses are taken every year. Thanks to these drugs, millions of men regained sexual confidence and again became sexually active.

Erectile tissue in nose lying

When it comes to erectile tissue, people often think about the sexual arousal. However, the tissue can also be an indicator of whether you tell the truth. When a person is lying, the erectile tissue in his nose is actively supplied with blood. As a result, the liar’s nose becomes red.

Erectile tissue is a part of not only the genitals in both men and women. The tissue is also located deep in the mucosa of inferior turbinates that are located on the lower edge of the middle turbinate in the posterior areas of the middle and upper turbinates.

The erectile tissue in the nose acts as a kind of air conditioning unit:

  • it provides blood supply to the glomus vessels;
  • it allows you to feel a variety of scents and flavors;
  • it plays an important role in the regulation of air temperature and humidity, directed into the lungs.

Telling lies requires large amounts of mental effort. When a person tells a lie, he experiences psychological and emotional excitement. Stress creates additional burden for many systems of the body, including the nervous and cardiovascular system.

Lies in conjunction with emotional stress contribute to the heart rate increase. Enhanced heart function increases blood flow to all organs of the body. No other organ of the human body is supplied with blood in such abundance, as the nasal cavity.

The erectile tissue plays the main role in blood supply of the nasal cavity. Redness of the turbinates is a sign of excessive blood supply to the erectile tissue in the nose. You can identify a lying person by such features, as:

  • redness of the nose;
  • touching the nose, scratching;
  • shortness of breath, nasal congestion, sneezing.

Itchy nose, sneezing and shortness of the liar’s breath is explained by the release of histamine, which occurs due to the increased blood supply to the turbinates. Increased blood pressure leads to a release of adrenaline. External signs of elevated adrenaline levels are reddening of the face (especially the nose), anxiety, and stress.

Redness of the nose is not only a sign that a person tells a lie. Violation of the tone of blood vessels of the erectile tissue in the nose can cause a number of the upper respiratory tract diseases, the most serious of which is idiopathic rhinitis.

Vasospasm of the erectile tissue in the nose and the appearance of the idiopathic rhinitis occur under the influence of the sympathetic nervous system. The activity of the sympathetic nervous system increases during exercise, and leads to a contraction of the erectile tissue in the nose and an increase of airflow volume that passes through the nose. The influence of impulses from the parasympathetic nervous system leads to vessels dilation of the erectile tissue in the nose.

Causes and risk factors of idiopathic rhinitis include:

  • cold;
  • cold-related diseases;
  • deformation of the nasal septum;
  • excessive alcohol consumption;
  • antihypertensive drugs;
  • hormonal changes during pregnancy.

In concomitant risk factors, the vessels of the erectile tissue in the nose dilate, when the body is in a horizontal position. The overcharging of vessels with blood in a lying person leads to a sharp enlargement of the mucous membrane thickness and the size of the turbinates. At the same time, the permeability of the capillary walls increases and blood plasma penetrates into the space between the mucosal cells.

Troubled nasal breathing is associated with impaired blood supply to the erectile tissue in the nose. Lying person often gets nasal congestion of either one or another side of the nose. A s a rule, the congestion of one or the other nostril manifests when a person is lying on his side, or changes the body position.

Blood supply of the erectile tissue in the nose increases in a lying person, and the blood rushes to the nasal cavity. Vessels of the erectile tissue in the nose that are in a relaxed state, due to loss of tone, overflow with blood, which causes a nose congestion. When you change your body position, congestion switches to the other side.

In the supine position, the mucosa rapidly fills with fluid, which results into a swelling. As a result, the lying person can breathe only through his mouth. As soon as he takes the upright position, mucosal swelling subsides quickly and the nasal breathing restores.

An expressed enlargement of the nasal cavities, in which the difficulty of nasal breathing is already clearly noticeable, is a pathological condition, and namely, the neurovegetative form of the idiopathic rhinitis.

Violation of airflow in the upper respiratory tract is a major clinical problem. Violation of the blood supply to erectile tissue in the nose causes breathing difficulties, sleep disturbances, and reduced life quality.

Idiopathic rhinitis is very dangerous for infants. Since babies spend most of their lives in a lying position, the erectile tissue in their nose is often overloaded with blood.

Because of the narrowness and the small size of the nasal cavity, even a slight swelling of the mucosa in newborns causes disturbance or complete cessation of nasal breathing. The reduction of the nasal airflow results in a dramatically more difficult and impossibility of breastfeeding, disturbed sleep, weight loss and restlessness of the newborn.

To improve nasal breathing and treat the symptoms of the idiopathic rhinitis, doctors use drugs, called nasal decongestants. Medications provide a temporary improvement of the nasal patency and decrease the tone of the vessels of the erectile tissue in the nose. One to three drops of the drug should be instilled into each nostril of the lying person, at the intervals of 4-6 hours.

Erectile tissue expanding foods

Many men are concerned about size of their penis and wonder whether foods can help in erectile tissue expanding or not. This is not surprising, because the modern pace of life and quality of food adversely affect the body and erectile function.

Today, there are many different methods for penile erectile tissue expanding. Foods, special exercise, hormonal drugs can be included in these methods. How versatile and safe are these methods? Are they suitable for all men without exception?

Everyone knows that foods that we consume every day affect the body functioning, as well as potency. Recent scientists’ studies have shown that high-quality foods also affect erectile tissue and can contribute to their expansion in volume.

Primarily researchers note ripe fruits and vegetables as erectile tissue expanding foods. Consumption of watermelons helps to increase the penis size and duration of erection.

Watermelon contains α-amino acid Citrulline, which is a precursor for arginine (an amino acid that promotes relaxation and elasticity of blood vessels).

Citrulline improves process of processing of ammonia and nitric oxide metabolism, opens the arteries increasing blood flow to the organs and systems.

The scientists concluded that watermelons belong to erectile tissue expanding foods and can be used to increase potency. In certain cases, watermelon can be an analog of drugs used to treat erectile dysfunction.

Vitamins positively affect men’s erectile function. Foods rich in vitamins promote blood flow to the erectile tissue and cause it expanding in volume.

Today, increase in erection is based on substantiated scientific evidences and studies. In particular, it comes to importance of vitamins B, A, and E for normal erection.

Foods containing these vitamins contribute also to enhanced transmission of nerve impulses that leads to increased sexual arousal.

Erectile tissue expanding foods containing vitamins include different types of leafy green vegetables, such as parsley, spinach, turnip, and Swiss chard.

If to regularly use these greens, whether in the form of a variety of juices, smoothies or in vegetable salads, your body will replenish with essential vitamins and minerals.

Moreover, the body detoxification can be carried out by means of leafy green vegetables that immediately have a positive effect on the cardiovascular system.

Healthy and elastic vessels are a pledge of full and stable erection. They contribute to a better blood flow in the erectile tissue and rapid onset of erection.

Garlic and ginger belong to foods contributing to expanding of erectile tissue. Effect of garlic on potency is due to its ability to activate the blood stream due to improvement of circulatory systems: arterial and venous.

This provides blood flow to cavernous body of the penis. Garlic, which is rich in Allicin also improves blood circulation and increases energy.

Garlic effect on potency directly depends on method of its use. In improper use, you can get an opposite result.

A number of studies have shown that fresh chopped garlic is effective for prevention of cardiovascular diseases, but dried garlic – for potency increase.

Ginger is considered one of aphrodisiac foods. It improves blood circulation in the pelvic organs, promotes arteries expansion and erection improvement.

Chemical composition of ginger consists of many useful substances: vitamins (of B, A, C groups), micro- and macronutrients (potassium, magnesium, sodium, iron, and calcium), and antioxidants.

Nuts, such as almonds, pistachios, cashew, walnut occupy a special place among large number of erectile tissue expanding foods. Each of them is rich in vitamins E, B, zinc, magnesium, folic acid. Thanks to its rich composition, nuts have a positive effect on sexual function.

Amino acid arginine contained in nuts activates production of nitric oxide, relaxes blood vessels and improves blood flow to erectile tissue.

Currently, almost all scientists agree with beneficial properties of Omega -3 and Omega-6 fatty acids. Many experts believe that foods high in fatty acids contribute to erectile tissue expanding and beneficially affect men’s health in general.

The human body does not produce omega-3 and omega-6, so it is very important the availability of these acids in men’s diet. Fatty acids are better absorbed from natural foods, rather than from dietary supplements.

Consumption of foods, rich in fatty acids, increases level of the hormone testosterone, which in turn has a positive effect on male sexual function and increases libido.

Seafood (oysters, lobster, and shrimps) and such fish varieties as salmon, trout and tuna are recognized the best sources of Omega-3 fatty acids.

The question regarding what erectile tissue expanding foods are the most useful and effective is still being studied by scientists. By including the above-mentioned foods in your diet, you will be able to achieve not only penis increase, but also to significantly improve erection.

The main thing in this case, follow the principle of the golden middle and not to abuse, otherwise the opposite effect can be obtained.

Erectile tissue definition

Erectile tissue plays an important role in the onset of sexual arousal in both men and women. To understand the process of sexual arousal, it is necessary to know the erectile tissue definition, as well as the characteristics and functions of the male and female reproductive system.

The medical dictionary can give you the anatomical definition of erectile tissue, which is as follows: vascular tissue, which becomes denser due to the dilation of numerous blood vessels.

Depending on gender, erectile tissue can perform a variety of functions:

  • in the male reproductive system – the blood flow to the penis and the onset of an erection;
  • in the female reproductive system – compression of the urethra and prevention of urination during intercourse.

Without the medical terminology, we can formulate the definition of erectile tissue in simple words: tissue that increases in volume in response to sexual stimulation.

The penis tissue is composed of three parts: the first two are pair of cavernous bodies, and the third part is the spongy body.

The process of erection involves all three of the penis bodies. The corpus cavernosa fill with blood, which makes the penis swell and become rigid. A large number of elastic fibers that the spongy tissue contains provide stretching and contraction of the urethra in urination and ejaculation.

Erectile tissue is an integral part of both male and female sexual organs. The main part of the clitoris consists of the double erectile tissue. It is located along the lower branches of the pubic bones. Just as it happens in the male penis, the clitoris tissue enlarges in volume during sexual arousal.

After the sexual excitement, the vagina is covered with erectile tissue on both sides. Along with the pubococcygeus muscle, this tissue compresses the urethra, thus preventing urination during sexual activity.

The erectile tissue in both the penis and the clitoris is incapable of constricting, like the vessels. Therefore, any slight tissue damage creates a risk of excessive bleeding.

While defining the erectile tissue, the sexual arousal in men and women is not the only thing to be considered. Erectile tissue is not only part of the penis, but also of the nose and ears.

Blood flow to the erectile tissue can cause not only sexual arousal, but a nasal congestion, as well. Cavernous venous plexus are located under a layer of the nasal mucosa. Plexus is a tangle of dilated veins, the walls of which are rich in smooth muscle and contain elastic fibers.

In insufficient blood supply, the vessels of the turbinates cavernous tissue are relaxed. However, under the influence of a wide variety of physical, chemical, infectious or psychogenic factors, the erectile tissue fills with blood, which immediately leads to swelling of the mucous lining.

Inadequate constriction and dilation of erectile tissue in the nasal cavity is one of the mechanisms of vasomotor rhinitis development. When the cavernous venous plexus expand and fill with blood, the thickness of the mucous membrane increases sharp. Turbinates may swell so much that they close the nasal passages. This results into the obstruction of nasal breathing.

The American surgeon, John McKenzie, was the first to attempt formulating the erectile tissue definition in the context of the relationship between the nasal cavity and the genitals. While studying the neurological reflexes, McKenzie offered the term “nasogenital reflex” in 1883. According to the hypothesis of the medical professional, nasal congestion can cause problems with sexual health (such as pelvic pain, dysmenorrhea, etc.) and vice versa.

The German otolaryngologist, Wilhelm Fleiss, expanded McKenzie’s theory. In 1893, the doctor suggested that the expansion of blood vessels in the nasal erectile tissue can cause not only sexual dysfunction, but also a variety of other disorders, like insomnia, migraine, asthma, stomach pain, etc.

The term “nasogenital reflex”, which was suggested by McKenzie to explain the relationship between sexual activity and nasal congestion, was not accepted by the official Otolaryngology. Hypotheses by McKenzie and Fleiss did not receive a sufficient amount of evidence, and remained just a theory.

The erectile tissue definition suggests that the tissue plays both a positive and a negative role in a person’s life:

  • blood flow and expansion of the tissue in the genital organs is necessary for a full sexual intercourse;
  • dilation of blood vessels in the nasal cavity often leads to congestion or complete obstruction of the nasal sinuses.

Sexual arousal and sexual intercourse are impossible without the involvement of the erectile tissue. Definition of sexual arousal is as follows: changes in the body that occur under the influence of sexual stimuli. Excitation precedes the moment of the very sexual intercourse beginning.

Occurrence of rhinitis and other upper respiratory tract disorders is a direct consequence of the erectile tissue activity in the nasal cavity. The tissue is a powerful vascular bed, which provides an abundant blood supply to the nasal area.

Erectile dysfunction pumps for sale

Erectile dysfunction pumps are some of the first means that have been used for treatment of erectile disorders. If you experience such disorders, try a vacuum therapy. Despite the apparent simplicity, this type of treatment is much more effective than some men expect.

Currently, there are hundreds of different erectile dysfunction pumps for sale. Today, you can find simple hand-held devices or motorized systems with electronic control.

Nevertheless, all vacuum constriction devices have three main components:

  • Cylinder, in which the penis is placed.
  • Pump – to create a low air pressure.
  • Tension band – to hold the blood in cavernous body.

These components are rarely the only things in a kit with erectile dysfunction pumps. Kits for sale may include DVD-video training, instruction manual, lubricant, battery pump, cylinders and tension bands of different sizes.

Different modifications of erectile dysfunction pumps have identical mechanism of action and sequence of using the device:

  • The penis is placed into the cylinder hole of the vacuum pump.
  • The air is removed from the cylinder until a needed pressure.
  • Low pressure is created and cavernous bodies are passively filled with the blood.
  • The penis increases in size, it becomes hard and erect.
  • Tension band is set at the penis base.
  • Cylinder pressure is equalized to atmospheric.
  • After sexual intercourse, tension band is removed.

Effectiveness of erectile dysfunction pumps is comparable to that of erectile dysfunction treatment pills (e.g., Viagra or Cialis). The vast majority of men (80%-90%) are satisfied with the results of using vacuum erection devices.

Vacuum therapy is not only effective, but also safe treatment method of erection problems. The doctor’s prescription is not required to buy such devices. Erectile dysfunction pumps are available for sale at pharmacies and in usual stores.

However, erectile dysfunction pumps may cause side effects especially if they are misused. Prolonged exposure of excessively low air pressure on the penis tissues may cause small hematomas.

Most vacuum constriction devices have a valve, which automatically operates when a big difference between pressure inside the tube and atmospheric pressure is created. Use of such devices minimizes risk of hematomas and other side effects.

Before to buy a favorite model of erectile dysfunction pumps, ensure that it is equipped with an automatic valve. These penis vacuum pumps can have manual and automatic valves.

Today, you can find a variety of erectile dysfunction pumps for sale. Price of vacuum constriction devices depends on model and place of purchase.

  • Price of the most simple hand pumps makes $ 15.
  • Price of automatic ED pumps varies from $ 80 to $ 500.

Price of one Viagra 100mg pill is several times higher than that of the most simple vacuum erection devices in the United States. Price of small packaging of Viagra is the same as that of the most expensive erectile dysfunction pumps.

One Viagra pill causes erection only once or several times within 4 hours after intake. Erectile dysfunction pumps work for many years. Some manufacturers give a lifetime warranty on their products.

Today, there are many places where erectile dysfunction pumps are available for sale. However, the main sales of vacuum devices are carried out online. This is connected with the fact that:

  • Many men are shy to buy erectile dysfunction pumps personally.
  • Online pharmacies offer a wide range of vacuum constriction devices and low prices.

Amazon, Walmart, Walgreens, and other online stores offer the best prices on erectile dysfunction pumps. On web sites of online stores, you can also:

  • Read men’s reviews, who used ED pumps;
  • Find out what brands are leading;
  • Select the best-selling vacuum constriction devices;
  • Ask any questions by email.

Today it is very easy to choose ED pump that is best suitable for you. The best erectile dysfunction pumps are available for sale on the first page of online store.

If you selected the pump model, you need to follow some simple steps:

  • Add selected ED pump in the basket
  • Specify the country and delivery address
  • Choose a delivery method
  • Choose a payment method
  • Pay the order

Standard delivery of erectile dysfunction pumps in the USA makes 4-5 working days. If the order price will exceed $ 30-40, the delivery can be free.

If you choose fast shipping, additional fee is charged. You pay about $ 15-20 for shipping and get the chosen erectile dysfunction pump within one day.

Today, erectile dysfunction pumps are available for sale for every taste. You can choose low-cost hand pumps or modern devices with a rechargeable battery.